Gene “sea election” to find the “resistance genes”
Posted on October 27, 2009
Filed Under Eye disease | Leave a Comment
High incidence of diabetic retinal disease, serious or even blindness. The news yesterday from the Zhongshan Ophthalmic Center, Sun Yat-sen exclusive informed that the center through genetic “sea election” to find some place to prevent diabetic retinopathy “resistance genes”, in the future of these resistance genes into the body in patients with diabetes is expected to enable patients with diabetes from the retinopathy trouble.
Diabetes-prone retinopathy
Zhongshan Ophthalmic Center, Sun Yat-sen, deputy director of China Institute of Ophthalmology, deputy head of the fundus Studies Professor Tang Shibo introduction, diabetic retinopathy is a serious eye disease that can cause blindness, but also a major complication of diabetes. At present, China 10-15 years with diabetes, the incidence of retinopathy was 25%; more than 20 years with diabetes, the incidence of retinopathy as high as 90%!
Professor Tang Shibo points out that diabetes patients with retinopathy, the first blurred vision, and then there shadow, vision loss and other disease, can lead to serious retinal detachment, eventually leading to blindness. “Early treat diabetic retinopathy, if blinding is not reversible by.”
“Sea election” to find “resistance genes”
Why are there diabetic retinopathy? Through research scientists have found that the incidence of diabetic retinopathy with the body’s immune response and vascular endothelial growth factor relevant. But why have some diabetic retinopathy soon after they fell sick, and some patients have arrived late, or even appear?
It turned out that some of the human body exist in a number of “resistance genes”, it will work with vascular endothelial growth factor to a negative adjustment to avoid the appearance of diabetic retinopathy.
In 2005, TANG Shibo led research team began the search for “resistance gene” research, the subject was the National Natural Science Fund. They will not suffer from a group of diabetic retinopathy in patients with a group of diabetic retinopathy in patients with genetic comparison, the success of “sea election” out of a part of the “resistance genes”, the demonstration of the ongoing animal models, have not yet entered clinical trials , while the research results will be the core of journals published in China. “This research ideas can be used to search for other complications of diabetes, the ‘resistance genes’, as well as the tumors ‘resistance genes’, so far-reaching significance.”
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