Treatment of diabetic nephropathy, “258″ Law
Posted on December 18, 2009
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Kidney fifth also be divided into three stages, creatinine is the best indicator of renal function, blood urea nitrogen by the impact of diet, eat tofu, or meat, blood urea nitrogen may be high, if the vegetarian diet, blood urea nitrogen index may be reduced, but the creatinine index will not be going down, creatinine another job means that the lesions occur in the kidneys. We have to remember that “258″ Law:
1. Renal function was normal creatinine is less than 2 represents the normal renal function;
2. Renal dysfunction than creatinine is less than 5 is called the two renal insufficiency;
3. Creatinine renal failure is higher than 5 and less than 8 is called renal failure.
Creatinine of more than 8 is uremia. Uremia renal insufficiency is actually the final stage, all systemic symptoms at this time, and at this time re-treatment at relatively late, nor is it even got to declare an immediate death of uremia, there are some ways the best approach is to early prevention. This is the method of diagnosis of diabetic nephropathy, and renal disease clinical manifestations and staging methods.
Related links: Diabetic nephropathy can be divided into five phases:
The first phase can be called the proliferative phase of high filtration. Hyperplasia is a kidney grow big, high-filter is the filter much more. Early diabetic nephropathy kidneys work very hard to make itself particularly large, is to go to the sugar discharge this heavy burden, the kidneys become large, there is no early symptoms.
The second phase is called pre-clinical. In fact this period also did not check out diabetic nephropathy, blood pressure and occasionally some people a bit high, normal blood pressure were not high, the pressure fluctuations caused by kidney disease is difficult to say, if at this time to do a kidney biopsy or puncture, can be found in kidney has changed, but the urine did not check out, there is no pre-clinical performance.
The third period is the early kidney disease. The beginning, some relatively fixed performance, a performance that is often high blood pressure, kidney itself is affected by the impact of blood pressure, high blood pressure also affect the kidney, forming a vicious cycle. In the search can be found in urine when the urine inside the protein began to appear. Early kidney disease is a very critical period, because this period, although there is no sense of kidney, but after treatment, kidney disease is completely reversible. Kidney to the fourth and fifth can not be reversed.
Early kidney disease can be diagnosed by urine protein check. Some people do not check urine protein lifetime, and some people only use check urine sugar test paper, I personally believe that search does not check urine sugar does not matter, because urine and blood glucose do not match. We can think about is the impact of urine, blood, body, or affect the body? Of course, affect the body of blood. The second issue to consider is the urine is not affected by the impact of drinking water, drink some water have less urine, less water, urine concentration, and urine will be high, so urine does not necessarily reflect the true value of the problem. The key issue is to check urine protein, urine routine can check that this protein is very rough, often early diabetic nephropathy by urine routine check does not check out, so to investigate the urinary microalbumin, which is the most important early diagnosis of kidney disease , and the best indicator. General recommendation for six months or a year once a urine microalbumin check if we went into the third phase is necessary to take therapeutic measures. Phase III is often high blood pressure, not the occasional high blood pressure fluctuations that reflect the progress of kidney disease. This period the blood has never made out of waste, but also the extent permitted by, for example we can row 100%, now only 80% of the row, this time check urea nitrogen, creatinine also do not see the problem, but the ability of renal has declined.
Phase IV is a period of clinical nephrology. A large number of proteinuria, at any time check, at any time, but particularly large amount, regardless of what measures, which proteinuria has not completely disappeared. Sustained increases in blood pressure, kidney, urea nitrogen, creatinine also increased, this situation is irreversible. We call the clinical kidney disease, the symptoms of this period is not yet particularly evident. If the fourth did not receive effective treatment, renal function continued to decline, the blood inside creatinine, blood urea nitrogen because it did not break out, they have risen.
The fifth is the period of renal insufficiency. This period are more symptoms, like high blood pressure, edema, multiple urine or urine does not come out, whole body pain (including low back pain). Some people waist got a pain that it is the kidney, this understanding is unscientific. Back pain may not have kidney disease, kidney disease is not necessarily back pain. Waist is mainly bones, joints and soft tissues, the real kidney does not necessarily show symptoms of back pain. In addition, there are other symptoms, such as anemia (kidney hematopoietic function as demonstrated in its pale, panting, physical weakness), osteoporosis (calcium metabolism of renal effects), osteoporosis patients Paipian Zi will find the bones in particular cakes, and prone to fracture.
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